| |
Composition
Bicotrim Tablets:
Bicotrim 120
Sulphametoxazole 100mg+ Trimethoprim 20mg
Bicotrim 480
Sulphametoxazole 400mg+ Trimethoprim 80mg
Bicotrim 960
Sulphametoxazole 800mg+ Trimethoprim 160mg
Bicotrim Suspension:
Each 5 ml contains Sulphametoxazole 200mg+ Trimethoprim 40mg
-----------------------------------------------------------------------------------------------------------------------------
Indications
- Urinary tract infections
- Acute otitis media in paediatric patients
- Acute exacerbations of chronic bronchitis in adults
- Traveller’s Diarrhoea in adults
- Pneumocystis carinii pneumonia
-----------------------------------------------------------------------------------------------------------------------------
Dosage and Administration
Bicotrim should be taken with fluid, preferably after a
meal. Adequate fluids should be taken when on Bicotrim. The
patient should notify the physician of skin rash, sore
throat, fever or unusual bruising or bleeding.
-----------------------------------------------------------------------------------------------------------------------------
Adults and children (above 12 years)
Contraindicated in pediatric patients less than 2 months of
age.
Urinary Tract Infections and Shigellosis in adults and
pediatric patients and acute otitis media in pediatric
patients.
-----------------------------------------------------
Adults
The usual adult dosage in the treatment of urinary tract
infections is 1 Bicotrim tablet, or 4 teaspoonful Bicotrim
suspension every 12 hours for 10 to 14 days. An identical
dosage is used for 5 days in the treatment of Shigellosis.
Acute Exacerbation of Chronic bronchitis
1 Bicotrim tablets, or 4 teaspoonful of Bicotrim
suspension every 12 hours for 14 days.
Travelers Diarrhoea
1 Bicotrim tablet, or 4 teaspoonful of Bicotrim
suspension every 12 hours for 5 days.
-----------------------------------------------------
Pediatric patients
The recommended dose for pediatric patients with urinary
tract infections and acute otitis media is 8 mg/kg
trimethoprim and 40 mg/kg sulfamethoxazole per 24 hours,
given in two divided doses every 2 hours for 10 days. An
identical daily dosage is used for 5 days in the treatment
of Shigellosis.
-----------------------------------------------------------------------------------------------------------------------------
Pneumocyst carinii pneumonia: Treatment
Adults and Paediatric Patients
The recommended dosage for treatment of patients with
documented Pneumocystis carinii pneumonia is 15 to 20
mg/kg trimethoprim and 75 to 100 mg/kg sulfamethoxazole per
24 hours given in equally divided doses every 6 hours for 14
to 21 days.
Prophylaxis
Adults
1 Bicotrim tablet daily.
Paediatric patients
The recommended dose is 150 mg/m 2 /day trimethoprim with
750 mg/m 2 / day sulfamethoxazole given orally in equally
divided doses twice a day, on 3 consecutive days per week.
The total daily dose should not exceed 320 mg trimethoprim
and 1,600 mg sulfamethoxazole.
Contraindications
Marked liver parenchymal damage, blood dyscrasias, severe
renal insufficiency and glucose 6-phosphate dehydrogenase
deficiency, known hypersensitivity to sulphonamides and/or
trimethoprim. Treatment must be discontinued on the
appearance of a skin rash, or if any element of the blood
count is reduced.
-----------------------------------------------------------------------------------------------------------------------------
Presentation
Bicotrim 120 Blister of 10 tablets
Bicotrim 480
Blister of 10 tablets
Bicotrim 960
Blister of 10 tablets
Bicotrim Suspension
Bottle of 100ml
back to top
----------------------------------------------------------------------------------------------------------------------------- |
|