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DEXAMETHASONE-AGIO SOLUTION FOR INJECTION

DEXAMETHASONE SODIUM PHOSPHATE INJECTION USP 2 ml (4mg/ml)

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Composition


Each ml of Injection contains:
Dexamethasone Sodium Phosphate USP
Equivalent to Dexamethasone Phosphate 4 mg
Methyl Paraben IP 0.15% w/v
(As Preservative)
Propyl Paraben IP 0.02% w/v
(As Preservative)
Water for Injection BP q.s.

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Indications

Dexamethasone sodium phosphate injection is indicated in the synovitis of osteoarthritis, rheumatoid arthritis including juvenile rheumatoid arthritis, acute and subacute bursitis, epicondylitis, acute nonspecific tenosynovitis, acute gouty arthritis, psoriatic arthritis, ankylosing spondylitis, pemphigus, herpetiformis, severe seborrheic dermatitis, severe psoriasis, mycosis fungoides, bronchial asthma, contact dermatitis, atopic dermatitis, serum sickness, severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa, ulcerative colitis, for palliative management of hypercalcemia associated with cancer, leukemias and lymphomas in adults, acute leukemia of childhood.

Dexamethasone injection may be used to treat patients with cerebral edema from various causes.


Dosage and Administration

Usual adult dose ranges from 0.5 to 20 mg daily depending on the severity of the disorder.
Dexamethasone injection may be administered intravenously or intramuscularly.
The parenteral administration must be reserved for administration in emergencies or ad intensive therapy.

Intra-articular (depending on the size of the joint), intralesional, intra-muscular or soft-tissue injection: 0.8 to 4 mg.


Contraindications

Unless considered life-saving, systemic administration of dexamethasone is contraindicated in systemic viral and fungal infections and in patients with peptic ulcer, osteoporosis and psychoses. Dexamethasone is also contraindicated in patients who are hypersensitive to the drug or any component of the injection.

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Presentation

Vial of 2.0 ml


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