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CEFOPAM 1 g
POWDER FOR PREPARATION OF INJECTION SOLUTION
(Sulbactam & Cefoperazone For Injection)
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Composition
Each Vial contains:
Sulbactam Sodium USP equivalent to Sulbactam : 500 mg
Cefoperazone Sodium USP equivalent to Cefoperazone : 500 mg
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Indications
The combination of Cefoperazone sodium and Sulbactam sodium
is indicated for the treatment of the following infections
caused by susceptible organisms.
Respiratory tract infections (Upper and Lower), Urinary
Tract Infections, Peritonitis, Cholecystitis, Cholangitis
and other intra-abdominal infections, Bacterial sinusitis,
Meningitis, Skin and soft tissue infections, Bone and Joint
infections, Pelvic Inflammatory disease - endometritis,
gonorrhea and other infections of the genital tract.
Dosage and Administration
Adults:
The usual adult dose of the combination is 2 to 4 g/day
(i.e, 1-2 g/day each of Cefoperazone and Sulbactam) given IV
or IM in equally divided doses every 12 hours.
In severe or refractory infections the daily dosage may be
increased to 8g (i.e, 4g/day each of Cefoperazone and
Sulbactam) given IV in equally divided doses every 12 hours.
The recommended maximum daily dosage of Sulbactam is 4g (8g
of the combination).
Dosage regimens should be adjusted in patients with marked
decrease in renal function.
Children:
The usual dosage in children is 40-80mg/kg/day (20 to 40
mg/kg/day each of Cefoperazone and Sulbactam) every six to
twelve hours. In serious or refractory infections, these
dosages may be increased up to 160 mg/kg/idea of the
combination. (i.e., 80 mg/kg/day each of Cefoperazone and
Sulbactam) every six to twelve hours.
Contraindications
Allergy to Penicillin or Cephalosporin.
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Presentation
Vial of 1.0 gm
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